Analysis of disease markers of aging in physiological states
Correlation expression profiles of aging disease markers in 170 individuals aged 18-95 years
Aging disease marker specific-tissue transcriptomics data (from GTEx)
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Expression of ( proteomics of aging disease markers,SASP) by IR, RAS overexpression,and Atazanivir treatment
IR.
Senescence was induced by ionizing radiation (IR;10 Gy X-ray).
RAS overexpression.
RASv12 was cloned in pLVX vector to make inducible lentiviruses,
which were used to infect early.
Atazanivir treatment.
Cells were cultured in appropriate media containing 20 μMatazanavir,
which is a clinically relevant dose, or vehicle (DMSO) for 9 (early time point) or 14 days.
Aging disease marker specific-tissue transcriptomics data (from GTEx)
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Aging secretory proteomics dataset